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Methylthioadenosine nucleosidase : ウィキペディア英語版 | Methylthioadenosine nucleosidase
In enzymology, a methylthioadenosine nucleosidase () is an enzyme that catalyzes the chemical reaction :S-methyl-5'-thioadenosine + H2O S-methyl-5-thio-D-ribose + adenine Thus, the two substrates of this enzyme are S-methyl-5'-thioadenosine and H2O, whereas its two products are S-methyl-5-thio-D-ribose and adenine. This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is S-methyl-5'-thioadenosine adeninehyrolase. Other names in common use include 5'-methylthioadenosine nucleosidase, MTA nucleosidase, MeSAdo nucleosidase, and methylthioadenosine methylthioribohydrolase. This enzyme participates in urea cycle and metabolism of amino groups and methionine metabolism. ==Structural studies==
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes , , , , , and .
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